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AP Biology - Molecular Basis of Inheritance
Biology in Focus chapter 13
25 cards·by stewartreaches
transformation
A changer in genotype and phenotype due to the assimilation of external DNA by a cell.
Bacteriophage
A virus that infects bacteria; also called a phage
virus
An infectious particle incapable of replicating outside of a cell, consisting of an RNA or DNA
genome surrounded by a protein coat (capsid)
antiparallel
Referring to the arrangement of the sugar-phosphate backbone in a DNA double helix (they run
in opposite 5' > 3' directions).
semiconservative model
the two strands of the parental molecule separate, and each functions as a template for
synthesis of a new complementary strand.
Conservative model
The two parental strands reassociate after acting as template strands thus restoring the
parental double helix
Dispersive model
Each strand of both daughter molecules contains a mixture of old and newly synthesized DNA
Origins of replication
short stretches of DNA that have a specific sequence of nucleotides
replication fork
A Y-shaped region where the parental strands of DNA are being unwound.
Helicases
enzymes that untwist the double helix at the replication forks, separating the two parental
strands
Helicases
enzymes that untwist the double helix at the replication forks, separating the two parental
strands
single-strand binding proteins
bind to the unpaired DNA strands, keeping them from re-paring
Topiosomerase
relives the tight twisting of the strain ahead of the replication fork by breaking,
swiveling, and rejoining DNA strands
primer
The initial nucleotide chain that is produced during DNA synthesis, actually a short stretch
of RNA
primase
synthesizes the primer
DNA polymerase
catalyzes the synthesis of new DNA by adding nucleotides at the 3' end of a preexisting chain.
leading strand
The new complementary DNA strand synthesized continuously along the template strand toward
the replication fork in the mandatory 5'>3' way
lagging strand
a discontinuously synthesized DNA strand that elongates by mean of Okazaki fragments, each
syntheiszed in t a 5'-3' direction away from the
Okazaki fragments
fragments of nucleotides which are put together on the lagging strand
DNA ligase
enzyme which attaches all of the Okazaki fragments into a continuous DNA strand
nuclease
an enzyme which cuts out portions of DNA strands with replication errors
telomeres
a short nucleotide sequence of repetitions, which pospone the erosion of the ends of genes
nucleoid
dense region of DNA found in bacterium
chromatin
complex of DNA and proteins
heterochromatin
interphase chromatin visible as irregular clumps with a light microscope