Immunology

Test Your Skills

17 cards·by haagh

When looking at the immune system, what are some causes of infectious disease person to person?

Bacteria, Viruses and Parasites

When looking at the immune system, what are some causes of non-infectious diseases?

cancer, toxins and auto immune diseases

Does the system develop continuously over a lifetime or all at one time?

continuously

How many cells die a day?

50-70 billion

How does the lymphatic system move around your body since it has no pump?

combination of gravity and the movement of muscles from moving and breathing

Why do immune cells leave the blood?

Because infections are usually in the tissues!

Are macrophages long or short lived cells?

long lived

what are the three granules?

neutrophil, eosiniphil and basophil

Where to dendritic cells migrate from?

They migrate from tissues to lymph nodes and bring info about pathogens with them

What is immunology?

the study of physiological mechanism humans and other animals use to defend their bodies from invasion by other organisms

What is C3?

a key complement protein; is cleaved into two parts when activated

What is C3a?

cleaved part of the key complement protein; recruits phagocytes

What is C3b?

cleaved part of the key complement protein; has an exposed thioester that can react with hydroxyl or amino groups from proteins and carbohy

Explain the classical pathway

the third activated complement pathway; consists of both a innate and adaptive component

Explain the alternative pathway

first activated complement pathway; a rapid innate response to infection

What are macrophages?

dedicated phagocytes of myeloid lineage; long lived; work to coordinate the immune response

What are "V,D,J"

regions that encode the variable regions of Ig and TCR molecules