DM

1. unknown as idiopathic 2. Condition that directly damages cartilage or joint instability

1. Mild discomfort-great disability 2. Lead to loss of function 3. Affected by inclement weather 4. Crepitation 5. Deformity

Nodes are red, swollen, tender; Heberden's nodes; Bouchard's nodes

Salicylates, NSAIDS, Antibx, Topical Analgesics, Corticosteroids, Disease-Mod Antirheumatics, Immunsup, Biologic/targeted tx

Joint pain+stiff, ADLs, pain man + what works + duration; compare contralateral joint

Maintain/improve joint funct, joint protection, achieve self-care + maintain optimal funct, use meds + non-med strategies to manage pain

1 Health promotion 2 PT/OT 3 Admin meds + non-meds or therapies 4 Modify home environ to safety + acessibility

Chronic, systemic autoimmune disease; Inflam of CT of synovial joint; Peaks btw age 30-50; Women are affected 2-3x men

Unknown; AUtoimmune etiology is accepted (Rh Factor); Genetic factors

Early: No destructive changes on xray, possible evidence of osteoporosis

Moderate: Xray evidence of osteoporosis w or w/o slight bone or cartilage dam; No joint deform; Adjacent muscle atrophy + node presence

Severe: Xray evidence of cartilage + bone destruction in addition to osteoporosis; joint deformity; extensive muscle atrophy w nodule presen

Terminal: Fibrous or bony ankylosis

Increase in uric acid production; Underexcretion of uric acid by kidneys; Increase intake of foods containing purines

Hereditary (overproduction or retention of uric acid); 90% of cases

R/T another acquired disorder; result of drugs that inhibit uric acid excretion (Thiazide diuretics)

Na+ Urate crystal deposits

Inflammation of great toe

Hx + PE w family hx of gout; Serum uric acid level >6mg/dL; 24h urine; Synovial fluid aspiration; Xray normal in early stages

Colchicine, NSAIDS, Allopurinol, Febuxostat, ACTH (Adrenocorticotropic hormone Probenecid), Corticosteroids

Multisystem inflammatory autoimmune disease